ROSS: Hey! I just heard. What’s up?
DOCTOR: Kidney stones! Now, ordinarily Mr. Tribbiani, we try to break up the stones with shock waves, but they’re too close to the bladder now. Which means we can either wait for you to pass them or else go up the urethra…
JOEY: Whoa-whoa! No-no-no-no-no, nothing is going up! Okay? Up, up is not an option —- what’s a urethra?
[Monica whispers the answer in his ear] Are you crazy?!
Friends 5.03 - “TO Hundredth”